Sign up and activate
your Savings Card

Pay as little as $15* on each prescription fill, up to a maximum benefit of $90 on each 30-day prescription of Motegrity. This offer is valid for up to 15 fills, or until the program expires.

*Terms and conditions apply, please see details and restrictions below.

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Motegrity™ (prucalopride) Savings Card Motegrity™ (prucalopride) Savings Card

EnrollmentActivation Complete

Thank you for registering for aactivating your
Motegrity Savings Card

Your card is now ready to use.

A copy of your card has also been emailed to you.

Be sure to write down your 11-digit ID number and the numbers or characters for RxBIN and RxPCN in case you lose your card. Next time you get your prescription filled, present your card to the pharmacist for instant savings.*

You can also download your card here:


*Terms and conditions apply. Please see details and restrictions below.

*Terms and conditions apply. Please see details and restrictions below.

All fields are required except when marked optional

Step 1: Verify Eligibility


Step 2: Enter Personal Information

Submit Information

Terms & Conditions

Eligible Commercially Insured patients may pay as little as [$15] and receive up to [$90] off their co-pay or out of pocket expenses per 30 day supply of Motegrity™ (prucalopride). Offer valid for up to [15] uses through offer expiry. A valid Prescriber ID# is required on the prescription. Offer valid for patients ages 18 and older. [Offer not valid for cash paying patients.]

Patient Instructions: In order to redeem this offer you must have a valid prescription for Motegrity. Follow the dosage instructions given by the prescribing doctor. This offer may not be redeemed for cash. By using this offer, you are certifying that you meet the eligibility criteria and will comply with the terms and conditions described in the Restrictions section below, and understand and acknowledge the Shire Privacy Notice. Patients with questions about this offer should call [1-833-666-2499].

Pharmacist: When you apply this offer, you are certifying that you have not submitted a claim for reimbursement under any federal, state, or other governmental programs for this prescription. Participation in this program must comply with all applicable laws and regulations as a pharmacy provider. By participating in this program, you are certifying that you will comply with the terms and conditions described in the Restrictions section below.

Pharmacist instructions for a patient with an Eligible Third Party: Submit the claim to the primary Third Party Payer first, then submit the balance due to CHANGE HEALTHCARE as a Secondary Payer COB (coordination of benefits) with patient responsibility amount and a valid Other Coverage Code, (e.g. 8). The patient is potentially responsible for the first [$15] and the offer pays up to the next [$90]. Reimbursement will be received from CHANGE HEALTHCARE.

Valid Other Coverage Code required.

For any questions regarding CHANGE HEALTHCARE online processing, please call the Help Desk at [1-800-433-4893].

Restrictions: This offer is only valid for residents of the United States, Puerto Rico and U.S. Territories. Offer not valid for prescriptions reimbursed under Medicaid, a Medicare drug benefit plan, Tricare, or other federal or state health programs (including any state medical assistance program) or where prohibited by the health insurance provider. Cash Discount Cards and other non-insurance plans are not valid as primary under this offer. If the patient is eligible for drug benefits under any such program, the patient cannot use this offer. By using this offer, the patient certifies that he or she will comply with any terms of his or her health insurance contract requiring notification to his or her payor of the existence and/or value of this offer. Offer not valid for patients under 18 years of age. It is illegal to (or offer to) sell, purchase, or trade this offer. Program expires [12/31/2019]. If your insurance situation changes, it is your responsibility to notify [customer service at 1-833-666-2499]. This offer is not transferable and is limited to one offer per person and may not be combined with any other coupon, discount, prescription savings card, rebate, free trial, patient assistance, or other offer. Not valid if reproduced. Void where prohibited by law. Program managed by ConnectiveRx on behalf of Shire US Inc. The parties reserve the right to discontinue, rescind, revoke or amend this offer without notice at any time. This is not health insurance.

What is Motegrity?

Motegrity is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). Idiopathic means the cause of the constipation is unknown. It is not known if Motegrity is safe and effective in children.

Important Safety Information

Do not take Motegrity if you:

  • are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.
  • have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease, ulcerative colitis.

Before taking Motegrity, tell your healthcare provider (HCP) about all of your medical conditions, including if you:

  • have or have had depression, suicidal thoughts or actions, or mood problems
  • have kidney problems. Your HCP may give you a lower dose
  • are pregnant or plan to become pregnant. It is not known if Motegrity will harm your unborn baby
  • are breastfeeding or plan to breastfeed. Prucalopride can pass into your breastmilk. Talk with your HCP about the best way to feed your baby if you take Motegrity.

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Motegrity?
Motegrity may cause serious side effects, including:

  • unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your HCP immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.

The most common side effects of Motegrity include:

  • headache
  • stomach area (abdominal) pain or bloating
  • nausea
  • diarrhea
  • dizziness
  • vomiting
  • gas
  • fatigue

These are not all the possible side effects of Motegrity. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit or call 1-800-FDA-1088.

Please click here for full Prescribing Information and Patient Information.