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Let’s get moving

Follow these simple steps and you'll be on your way. And if you still have questions, see the Motegrity FAQs below.

Ready to ask your
doctor about Motegrity?
Let's move!

1. Schedule your appointment

It's a date! Mark your calendar and you're ready to discuss Motegrity, the prescription medicine for adults with Chronic Idiopathic Constipation (CIC) that increases the rhythmic movements of your colon muscle. Chronic means having symptoms for at least 6 months. Idiopathic means the cause of the constipation is unknown.

Here's a useful tool to help guide you through the discussion.

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2. Note your symptoms

Your doctor will want to know what may or may not be working with your current treatment plan, so it's best to keep track.

3. Learn some new lingo

If you haven't already, brush up on How Motegrity Works and prepare any questions you may have.

Piggy bank

4. Sign up for savings

Treatment shouldn't have to strain your budget. Click here to see the savings offer for Motegrity.

5. Digest the FAQs

Motegrity works differently for adults with CIC, so we get all sorts of questions. Read through our most frequent answers here.

Select Important Safety Information

Do not take Motegrity if you:

  • are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.
  • have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn's disease, ulcerative colitis.
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Talking to your doctor about Chronic Idiopathic Constipation

CIC can be difficult to put into words, so let this guide help you and your doctor talk about the issues specific to your CIC experience. If you're looking to change your current treatment approach, ask your doctor about the different medications available for CIC.

This should only take a few minutes.

Click here to download a blank discussion guide

The personal information you provide as part of this tool will be used solely to allow you to generate a discussion guide to share with your healthcare provider. Takeda and other third parties will not collect, store, or use the information you provide in connection with this feature of the Motegrity website for any other purpose.

Talking to your doctor

Talking to your doctor about Chronic Idiopathic Constipation

Talking to your doctor

CIC can be difficult to put into words, so let this guide help you and your doctor talk about the issues specific to your CIC experience. If you're looking to change your current treatment approach, ask your doctor about the different medications available for CIC.

This should only take a few minutes.

Click here to download a blank discussion guide

The personal information you provide as part of this tool will be used solely to allow you to generate a discussion guide to share with your healthcare provider. Takeda and other third parties will not collect, store, or use the information you provide in connection with this feature of the Motegrity website for any other purpose.

A smart

to save money

Terms and conditions apply. See link for details.

Frequently Answered Questions

  • Motegrity targets a receptor in your colon involved in natural movements of the colon muscle (known as peristalsis). You can learn more about how Motegrity works by clicking here.

  • While your results may vary, people who started Motegrity in clinical studies had their first complete bowel movement within 1.4 to 4.7 days, compared with 9.1 to 20.6 days for people taking placebo. Learn more about the results and what to expect here.

  • While everyone’s body is different, the effect of Motegrity on improved bowel movement frequency was maintained through the 12-week clinical studies. Learn more about the results and what to expect here.

  • One tablet of Motegrity should be taken once a day, anytime, with or without food (or exactly as directed by your doctor). It may help to follow a routine like “after breakfast” or “before bed” so you don’t forget. See more dosing information here.

  • Motegrity may cause serious side effects, including unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your healthcare provider immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.

    Common side effects of Motegrity include headache, stomach area (abdominal) pain or bloating, nausea, diarrhea, dizziness, vomiting, gas and fatigue. These are not all the possible side effects of Motegrity. Call your doctor for medical advice about side effects. Learn more about side effects and what to expect here.

  • Do not take Motegrity if you are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat. You should also not take Motegrity if you have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease or ulcerative colitis.

  • Sure are! Eligible patients may pay as little as $15 per 30-day prescription or $45 per 90-day prescription of Motegrity.* Learn more about Motegrity savings offer here.

    *Up to $90 max benefit per 30-day prescription; $270 max benefit per 90-day prescription. Terms and conditions apply. See link above for details.

  • Coverage questions can be complicated and individual coverage may vary. That’s why we made Motegrity Answers. One quick call to 1-844-447-2582 and a friendly professional may be able to help sort you out. Motegrity Answers is available Monday through Friday from 8 a.m. to 8 p.m. ET.

  • Need support? We’ve got you covered. Just call Motegrity Answers at 1-844-447-2582 for questions about savings program, benefits investigation, and prior authorization. Motegrity Answers is available Monday through Friday from 8 a.m. to 8 p.m. ET.

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Let's start by
looking into your treatment history.

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Step
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Now let's look into how CIC has affected you.

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Step
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Let's talk about lifestyle changes.

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You've made it to the end!

Just a few more questions and we're done.

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Complete!

You're all set!

Thank you for taking the time to complete this doctor discussion guide

WHAT IS MOTEGRITY?

Motegrity is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). Idiopathic means the cause of the constipation is unknown. It is not known if Motegrity is safe and effective in children.

Important Safety Information

Do not take Motegrity if you:

  • are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.
  • have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease, ulcerative colitis.

Before taking Motegrity, tell your healthcare provider (HCP) about all of your medical conditions, including if you:

  • have or have had depression, suicidal thoughts or actions, or mood problems
  • have kidney problems. Your HCP may give you a lower dose
  • are pregnant or plan to become pregnant. It is not known if Motegrity will harm your unborn baby
  • are breastfeeding or plan to breastfeed. Prucalopride can pass into your breastmilk. Talk with your HCP about the best way to feed your baby if you take Motegrity.

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Motegrity?
Motegrity may cause serious side effects, including:

  • unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your HCP immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.
The most common side effects of Motegrity include:
  • headache
  • stomach area (abdominal) pain or bloating
  • nausea
  • diarrhea
  • dizziness
  • vomiting
  • gas
  • fatigue

These are not all the possible side effects of Motegrity. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. 
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for full Prescribing Information and Patient Information.

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