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Let’s get
moving

Follow these simple steps and you'll be
on your way. And if you still have questions, see the Motegrity FAQs below.

Ready to ask your
doctor about Motegrity?
Let's move!

1. Schedule your appointment

It's a date! Mark your calendar and you're ready to discuss Motegrity, the prescription medicine for adults with Chronic Idiopathic Constipation (CIC) that increases the rhythmic movements of your colon muscle. Chronic means having symptoms for at least 6 months. Idiopathic means the cause of the constipation is unknown.

2. Note your symptoms

Your doctor will want to know what may or may not be working with your current treatment plan, so it's best to keep track.

3. Learn some new lingo

If you haven't already, brush up on How Motegrity Works and prepare any questions you may have.

4. Sign up for savings

Treatment shouldn't have to strain your budget. Click here to see the savings offer for Motegrity.

5. Digest the FAQs

Motegrity is the only treatment of its kind for adults with CIC, so we get all sorts of questions. Read through our most frequent answers here.

Select Important Safety Information

Do not take Motegrity if you:

  • are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.
  • have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn's disease, ulcerative colitis.

A smart

to save money

*Up to $90 max benefit per 30-day prescription. Terms and conditions apply. See link above for details.

Frequently
Answered Questions

How does Motegrity move the colon muscle?

Motegrity targets a receptor in your colon involved in natural movements of the colon muscle (known as peristalsis). You can learn more about how Motegrity works by clicking here.

How fast can Motegrity start providing results?

While your results may vary, people who started Motegrity in clinical studies had their first complete bowel movement within 1.4 to 4.7 days, compared with 9.1 to 20.6 days for people taking placebo. Learn more about the results and what to expect here.

Will the results fade away after a couple weeks?

While everyone’s body is different, the effect of Motegrity on improved bowel movement frequency was maintained through the 12-week clinical studies. Learn more about the results and what to expect here.

How do I take my Motegrity?

One tablet of Motegrity should be taken once a day, anytime, with or without food (or exactly as directed by your doctor). It may help to follow a routine like “after breakfast” or “before bed” so you don’t forget. See more dosing information here.

What are the possible side effects of Motegrity?

Motegrity may cause serious side effects, including unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your healthcare provider immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.

Common side effects of Motegrity include headache, stomach area (abdominal) pain or bloating, nausea, diarrhea, dizziness, vomiting, gas and fatigue. These are not all the possible side effects of Motegrity. Call your doctor for medical advice about side effects. Learn more about side effects and what to expect here.

Who should not take Motegrity?

Do not take Motegrity if you are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat. You should also not take Motegrity if you have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease or ulcerative colitis.

Are there any savings offers available?

Sure are! Eligible patients may pay as little as $15* for a 30-day prescription fill of Motegrity. Learn more about Motegrity savings offer here.

*Up to $90 max benefit per 30-day prescription. Terms and conditions apply. See link above for details.

Is Motegrity covered under my benefits?

Coverage questions can be complicated and individual coverage may vary. That’s why we made Motegrity Answers. One quick call to 1-844-447-2582 and a friendly professional may be able to help sort you out. Motegrity Answers is available Monday through Friday from 8 a.m. to 8 p.m. ET.

Is there a number I can call for support?

Need support? We’ve got you covered. Just call Motegrity Answers at 1-844-447-2582 for questions about savings program, benefits investigation, and prior authorization. Motegrity Answers is available Monday through Friday from 8 a.m. to 8 p.m. ET.

What is Motegrity?

Motegrity is a prescription medicine used in adults to treat a type of constipation called chronic idiopathic constipation (CIC). Idiopathic means the cause of the constipation is unknown. It is not known if Motegrity is safe and effective in children.

Important Safety Information

Do not take Motegrity if you:

  • are allergic to Motegrity. Allergic reaction symptoms may include trouble breathing, rash, itching and swelling of your face, lips, tongue or throat.
  • have a tear in your stomach or intestinal wall (bowel perforation), a bowel blockage (intestinal obstruction) or serious conditions of the intestinal wall such as Crohn’s disease, ulcerative colitis.

Before taking Motegrity, tell your healthcare provider (HCP) about all of your medical conditions, including if you:

  • have or have had depression, suicidal thoughts or actions, or mood problems
  • have kidney problems. Your HCP may give you a lower dose
  • are pregnant or plan to become pregnant. It is not known if Motegrity will harm your unborn baby
  • are breastfeeding or plan to breastfeed. Prucalopride can pass into your breastmilk. Talk with your HCP about the best way to feed your baby if you take Motegrity.

Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of Motegrity?
Motegrity may cause serious side effects, including:

  • unusual changes in mood or behavior, thoughts of hurting yourself, trying to hurt yourself, or suicide. Stop taking Motegrity right away and tell your HCP immediately if your depression gets worse, you feel sad, hopeless or begin to have thoughts of suicide, thoughts of hurting yourself or have tried to hurt yourself.

The most common side effects of Motegrity include:

  • headache
  • stomach area (abdominal) pain or bloating
  • nausea
  • diarrhea
  • dizziness
  • vomiting
  • gas
  • fatigue

These are not all the possible side effects of Motegrity. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please click here for full Prescribing Information and Patient Information.